Short Title:
CHOICE II study
Responsible HRP Element:
Human Health Countermeasures
Funding Status:
Completed - Task completed and produced a deliverable
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Procurement Mechanism(s):
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Aims:
CHOICE II, is a follow up from a previous study in response to an ESA AO-CONCORDIA in 2007. That earlier proposal "CHOICE" (here further designated as CHOICE I) was implemented and successfully completed at CONCORDIA between 2008 and 2011 (end of experiment). As a logical consequence from these first and integrative observations demonstrating significant changes in immune and neuroendocrine parameters in the overwintering crew members, we are now focussing on deepening our understanding of these first observations using novel functional and molecular tests and analyses. They will help to decipher some of the mechanisms of adaptation to confinement under hypobaric hypoxia.
Other Resources
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Yes
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Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
This study will provide a report on the long term-confinement and hypobaric hypoxia on immunity. The report will contribute to gap closure by addressing the effect of long term-confinement and hypobaric hypoxia on immunity.
Internal Customers:
None
External Customers:
None