Task Comparing Globe Distortions Following Head-Down Bed Rest to those Measured in Astronauts in Short and Long-Duration Spaceflights [Thirty-day CO2 Bedrest/ALPERIN/ACTIVE]
Last Published:  07/31/19 10:05:33 AM (Central)
Short Title: Thirty-day CO2 Bedrest - Alperin
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Behavioral Health & Performance (BHP) Element
Other:
Funding Status: Terminated - A formerly active task that was stopped before its completion date due to deselection, descoping, reorganization etc.
Procurement Mechanism(s):
Solicited
Aims:
1. Use novel technology that quantifies the degree of the globe distortions by MRI to assess the efficacy of head-down bed rest as a ground-based analog for VIIP. Detect and measure the magnitude of changes in globe flattening, optic nerve protrusion, visual acuity, and other related imaging measures that might be induced by subjects undergoing 30 days of head-down bed rest. The magnitude of the changes observed in bed rest will be compared to those measured in astronauts with and without signs of the VIIP syndrome.

2.  Assess the efficacy of bed rest as a behavioral, health, and performance stressor. Neurocognitive tests, some of which are similar to those performed aboard ISS, will be administered to the subjects and compared to available data from ISS to determine the efficacy of the bed-rest model as a ground-based analog for cognitive and behavioral modifiers.
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