Task The impact of an ISS mission on the anti-viral and functional properties of NK-cells, T-cells, B-cells and dendritic cells (Simpson) Functional immune
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: Anti-viral and functional properties of immune cells
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):

[A] Determine the in-flight status of immune dysregulation (innate + adaptive) in conjunction with relevant parameters from other disciplines (nutrition, radiation, virology, host-pathogen, stress, etc.).

[B] Determine the post-flight time course to full recover for dysregulated parameters.

[C] Derive a final refined monitoring strategy encompassing innate immunity, adaptive immunity and relevant parameters from other disciplines which will be appropriate to validate countermeasures.

Integration/Unique Aspects: functional immune is a hybrid study that incorporates a directed portion with solicited portions.