Last Published:  07/30/20 02:45:15 PM (Central)
Short Title: Mars 600/900 Sim II
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Planned-Funded - Task expected to be within budget
Procurement Mechanism(s):
Solicited
Aims:



Specific Aims:

  • Aim 1 (Cancer): Determine impact of a simulated 600 day Mars mission exposure on radiation carcinogenesis including tumor burden, spectrum, latency, progression, and aggressiveness.

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  • Aim 2 (Cancer): Determine impact of a simulated 900 day Mars mission exposure, including complex secondary environment found on Mars Surface, on radiation carcinogenesis including tumor burden, spectrum, latency, progression, and aggressiveness.

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  • Aim 3 (CVD/CNS): Determine impact of a simulated 600 day Mars mission exposure on cardiovascular and late neurodegenerative CNS diseases.

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  • Aim 4 (CVD/CNS): Determine impact of a simulated 900 day Mars mission exposure, including complex secondary environment found on Mars Surface cardiovascular and late neurodegenerative CNS diseases.

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  • Aim 5 (Cross Risk): Validate biomarker approaches for in mission surveillance during Mars 600 and 900 mission simulation.

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Studies will focus on doses and dose rates seen on a 600 day free space transit simulating Mars flyby or opposition-class, short stay mission as well as a 900 day conjunction-class, long stay mission on the surface of Mars.




Resources (None Listed)
Mappings
RiskRisk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
You are here!TaskMars 600/900 Simulation II: Large Animal Chronic Studies

RiskRisk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
You are here!TaskMars 600/900 Simulation II: Large Animal Chronic Studies

RiskRisk of Cardiovascular Disease and Other Degenerative Tissue Effects From Radiation Exposure and Secondary Spaceflight Stressors
You are here!TaskMars 600/900 Simulation II: Large Animal Chronic Studies

RiskRisk of Radiation Carcinogenesis
You are here!TaskMars 600/900 Simulation II: Large Animal Chronic Studies

RiskRisk of Spaceflight Induced Cardiovascular Disease
You are here!TaskMars 600/900 Simulation II: Large Animal Chronic Studies