Task Mitigating radiation-induced bone loss via dietary modulation of inflammatory cytokines (Bloomfield) (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: radiation bone resorption dietary CM
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:

Determine alterations in bone structural integrity (density, geometry,

microarchitecture, mechanical properties), bone cell activity and osteocyte TNF-α, RANKL,

and sclerostin in mice exposed to low dose HZE radiation.

Determine impact of a diet high in omega-3 fatty acid content on osteocyte

TNF-α and decrements in bone structural integrity after exposure to low dose HZE radiation.


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