Short Title:
Tissue-Mitochondrial CV
Responsible HRP Element:
Space Radiation
Funding Status:
Active - Currently funded and in progress
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Procurement Mechanism(s):
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Aims:
Aim 1: To histologically analyze cardiac morphology and cardiac oxidative stress of mice
exposed to space radiation.
Aim 2: To appraise the levels of mitochondrial oxidative stress in response to space radiation.
Aim 3. To determine the status of mitochondrial stress response pathways.
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
Annual and final reports. The study's goal is to provide data that will fill knowledge gaps about radiation-induced degeneration or injury to cardiac mitochondria, and the adaptive stress response mechanisms, which potentially promote or mitigate potential risks to the heart.
Internal Customers:
None
External Customers:
None