HRR - Task - HFBP Thresholds for Health & Operational Performance Permissible Outcome Limit (POL)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Risk of Intervertebral Disc Damage After Prolonged Spaceflight

Common Item(s)
	Risk of Injury from Dynamic Loads

Dose Tracker Application for Monitoring Crew Medication Usage, Symptoms and Adverse Effects During Missions

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Identification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions (Cardiometabolic Vulnerabilities-Shea, Active)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Effects of emotional stress on the cardiovascular system (Stress and CV Health-TBD, Planned)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Effects of Retronasal Smelling, Variety, and Choice on Appetite and Satiety

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Sensorimotor Assessment and Rehabilitation Apparatus: Procedures and Equipment (Schubert)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Robust Human-System Interface Design for Spaceflight-Induced Environments (Interface Design-Stone, Completed)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Inadequate Human-Computer Interaction

Information Presentation – Displays Development (Visual and Auditory)

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Information Presentation – Controls Technology Survey and Testing

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Information Presentation - Electronic Procedures and Fault Management

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Information Presentation – Human Performance Modeling

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Spaceflight Resource Management Training

Common Item(s)
	Risk of Performance Errors Due to Training Deficiencies
	TRAIN-01: We do not know which validated objective measures of operator proficiency and of training effectiveness should be used for future long-duration exploration missions. (Previous title: SHFE-TRAIN-01)

Medical Proficiency Training

Common Item(s)
	Risk of Performance Errors Due to Training Deficiencies

DEFERRED: Validation of Exploration Atmosphere Prebreathe Protocol

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Physiological Factors Contributing to Postflight Changes in Functional Performance (Bloomberg)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Development of Countermeasures to Enhance Sensorimotor Adaptation (Bloomberg)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Assessment of Operator Proficiency Following Long-Duration Spaceflight (Moore)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Galvanic Vestibular Stimulation (GVS) as an Analogue of Post-flight Sensorimotor Dysfunction (Moore)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Modeling and mitigating spatial disorientation in low g environments

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Enhancement of Spatial Orientation Capability of Astronauts on the Lunar Surface

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Sensorimotor Displays and Controls to Enhance the Safety of Human/Machine Cooperation During Lunar Landing (Lander D&C-Young, Completed)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Inadequate Human-Computer Interaction

Advanced Displays for Efficient Training and Operation of Robotic Systems (Robotic Systems-Oman, Completed)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Development of Countermeasures to Aid Functional Egress from the Crew Exploration Vehicle Following Long-Duration Spaceflight (Mulavara)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Just in Time Simulation Platform

Common Item(s)
	Risk of Performance Errors Due to Training Deficiencies

Displays and Controls Interfaces

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Assessing and Mitigating the Impact of Transmission Delays on Teleoperations

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Automation Interface Design Tools Development

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration
	HARI-03: We do not know how to quantify overall human-automation-robotic system performance to inform and evaluate system designs to ensure safe and efficient space mission operations. (Previous title: SHFE-HARI-03)

Assessment, evaluation, and development of methodologies, metrics, and tools available for use in multi-agent (human and robotic) teaming

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Human – Automation Interactions and Performance Analysis of Lunar Lander Supervisory Control

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration
	HARI-03: We do not know how to quantify overall human-automation-robotic system performance to inform and evaluate system designs to ensure safe and efficient space mission operations. (Previous title: SHFE-HARI-03)

Space Human Factors and Habitability MIDAS-FAST: Development and Validation of a Tool to Support Function Allocation

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Needs Assessment and Work Allocation Tools for Mission Operations and Procedures

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Recovery Data Mining: Relationship Between In-Flight Exercise and Postflight Sensorimotor Performance. (Reschke)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Usability Evaluation

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Performance Data Mining: Correlation Between Previous Performance Data with Clinical Observations. (Reschke)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Workload Tools and Guidelines

Common Item(s)
	Risk of Inadequate Mission, Process and Task Design
	MPTASK-01: We need methods and tools to collect measures of missions, process, and task performance. (Previous title: SHFE-TASK-01)

Spaceprint: Development and Validation of a Tool to Predict, Evaluate, and Mitigate Excessive Workload Effects

Common Item(s)
	Risk of Inadequate Mission, Process and Task Design
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	MPTASK-01: We need methods and tools to collect measures of missions, process, and task performance. (Previous title: SHFE-TASK-01)

Common Item(s)
	Risk of Inadequate Mission, Process and Task Design
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	MPTASK-01: We need methods and tools to collect measures of missions, process, and task performance. (Previous title: SHFE-TASK-01)

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration
	HARI-03: We do not know how to quantify overall human-automation-robotic system performance to inform and evaluate system designs to ensure safe and efficient space mission operations. (Previous title: SHFE-HARI-03)

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Semantic Language and Tools for Reporting Human Factors Incidents

Common Item(s)
	Risk of an Incompatible Vehicle/Habitat Design

SDBI 1904 - Human Factors Assessment of Vibration Effects on Visual Performance During Launch

Common Item(s)
	Risk of an Incompatible Vehicle/Habitat Design

Combined whole-body vibration plus G-loading influences on visual performance and operator ratings

Common Item(s)
	Risk of an Incompatible Vehicle/Habitat Design

Spinal Elongation and its Effects on Seated Heights in a Microgravity Environment

Common Item(s)
	Risk of an Incompatible Vehicle/Habitat Design

Space Craft Internal Acoustic Environment

Common Item(s)
	Risk of an Incompatible Vehicle/Habitat Design

Common Item(s)
	Risk of Inadequate Mission, Process and Task Design

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Inadequate Human-Computer Interaction
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Habitability-Human Factors and Habitability Assessment Tool

Common Item(s)
	Risk of an Incompatible Vehicle/Habitat Design

Space Radiation Risk Assessment Project-Cucinotta

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-CNS - 5: How can new knowledge and data from molecular, cellular, tissue and animal models of acute CNS adverse changes or clinical human data, including altered motor and cognitive function and behavioral changes be used to estimate acute CNS risks to astronauts from GCR and SPE?

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Sensory Stimulation Augmentation Tools (RR)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Hybrid Training - A Sensory Stimulation Countermeasure for Long Duration Space Exploration Missions

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Psychomotor Vigilance Test (PVT) on ISS

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Promoting stress tolerance, adaptability and behavioral health via enhancing exercise protocols for LDEM

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Objective Detection, Evaluation and Countermeasures for In-flight Depression

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Optical Computer Recognition of Stress, Affect and Fatigue During Performance in Spaceflight

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Objective Monitoring of Crew Neurobehavioral Functions (105-day Russian Chamber Study)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Neurobehavioral Conditions List for Exploration Missions (RR)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Asthenia Literature Review

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Voice Content Analysis Techwatch

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Detection & Prevention of Neurobehavioral Vulnerability to Space Radiation

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Evidence Review: Cognition in Long Duration Missions in Isolated, Confined and Extreme Environments

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Validation of Assessment Tests and Countermeasures for Detecting and Mitigating Changes in Cognitive Function During Robotics Operations

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Integrated Cognitive Assessment: Combining Measurement, System, and Mission

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Neurostructural, Cognitive, and Physiologic Changes During a 1-year Antarctic Winter-Over Mission

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Cognitive Performance and Stress in a Simulated Space Environment

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

The Prediction of the Onset of Anxiety Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

White Paper on the Onset of Depression

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Meta-Analysis of the effects of ICE environments

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Evidence Review on Identification of Psychosocial Characteristics in ICE Environments

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Growth and Resilience for Long Duration Exploration Missions(RR)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Effects of Well-Being on Performance in ICE Environments (RR)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Individual differences and adaptation to Isolated, Confined, and Extreme (ICE) environments (Research Requirements)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Self-Guided Depression Treatment on Long-Duration Spaceflights

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

A Multi-Media, Computer-Based, Self-Directed, Autonomous, Stress and Anxiety-Management Countermeasure

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Behavioral Issues Associated with Long Duration Space Missions: Review of Astronaut Journals

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Asynchronous Behavioral Health Treatment Techniques

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Immune Function Data Mining

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Sleep-Wake Actigraphy and Light Exposure During Spaceflight

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Environmental Factors Evidence Review

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Transition Actiwatch Protocol to Medical Operations

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

The Biological Basis of Emotional Support for Long Duration Exploration Missions (RR)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Determine best methods to maintain contact with astronaut social support network during pre-mission training (RR)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Risk Assessment – Task Performance, Teamwork, and Psychosocial Performance

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Techwatch for Sleep Monitoring Technologies for Long Duration Spaceflight

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Analog Validation Study of Team Measures

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Evidence Review on Biomarkers of Individual Vulnerabilities to Sleep Loss and Circadian Desynchronization

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

AD ASTRA: Automated Detection of Attitudes and States through Transaction Recordings Analysis

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Team Risk Standardized Measures Workshop

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Literature Review and Operational Assessment of Psychosocial Strategies related to BHP

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Automated Behavior and Cohesion Assessment Tools

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Developing, Maintaining, and Restoring Team Cohesion

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Operational Evaluation of Photic Countermeasure to Improve Alertness, Performance, and Mood during Nightshift Work on a 105-Day Study (105-day Russian Chamber Study)

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Literature Review and Operational Assessment of Monitoring Tools and Technologies related to BHP

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Literature Review and Operational Assessment of Countermeasures Related to BHP

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Countermeasure for Managing Interpersonal Conflicts in Space: A Continuation Study

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Serious Games for Team Training

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Risk of Performance Errors Due to Training Deficiencies

ANSIBLE: A Network of Social Interactions for Bilateral Life Enhancement

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Investigating the Influence of Personality on Performance Within the Astronaut Population

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Examination of Cultural Interactions Using Archival Data Footage on ISS

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Dynamic Team Role Allocation in Long Duration, Exploration Missions: Identification of Roles, Triggers, and Measurement Tools

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Risk of Performance Errors Due to Training Deficiencies

Optimizing Crew Performance in Long Duration Space Exploration: Best Practices for Team Training and Cohesion Measurement

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Enhancing team performance for exploration missions (NASA PI)

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Evaluation of Photic Countermeasures for Circadian Entrainment of Neurobehavioral Performance and Sleep-Wake Regulation Before and During Spaceflight

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Optimizing Light for Long Duration Space Exploration

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Literature Review and Operational Assessment of Training Strategies related to BHP

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Blue Light for Enhancing Alertness in Space Missions

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Facilitating the Synergistic Side of Cultural Diversity in LDSE: Identification of Challenges and Development of Cultural Training

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Risk of Performance Errors Due to Training Deficiencies

Characteristics of Light Exposure Necessary for Development of Optimal Countermeasures to Facilitate Circadian Adaptation and Enhance Alertness and Cognitive Performance in Space

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Crew Scheduling Tools

Common Item(s)
	Risk of Inadequate Mission, Process and Task Design
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Feasibility Pilot Study on Acute Biological and Behavioral Responses to the Solid State Lighting Modules for the International Space Station

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Crew Interactions and Autonomy During Long-Duration Isolation and Confinement (105-Day Russian Chamber Study)

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Testing solid state lighting countermeasures to improve circadian adaptation, sleep, and performance during high fidelity analog and flight studies for the International Space Station

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Develop and Implement Operational Ground Testing Protocols to Individualize Astronaut Sleep Medication Efficacy and Individual Effects (pilot study)

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Operational Ground Testing Protocols to Individualize Astronaut Sleep Medication Efficacy and Individual Effects

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Designing Individual Countermeasures to Reduce Sleep Disruption and Improve Performance and Alertness in Space

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Physiologically-Based Modeling of Sleep-Wake Scheduling and the Effects of Pharmaceuticals (NSBRI Postdoctoral Fellowship)

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Countermeasures for Performance Deficits from Sleep Loss and Workload in Space Flight

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Individualized Fatigue Meter for Space Exploration (SBIR Phase II)

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Countermeasures to Neurobehavioral Deficits from Cumulative Sleep Deprivation During Space Flight: Dose-Response Effects of Recovery Sleep Opportunities

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Survey of On-Orbit Sleep Quality (Sleep Quality Questionnaire)

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Phoenix Scout Lander: Countermeasures Testbed for Spaceflight Ground Controllers

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

A Comprehensive Fatigue Management Program and an Evaluation of a Photic Countermeasure for Mission Controllers

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Autonomy Literature Review Requirements

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Neurodegeneration and Adaptation in Response to Low-Dose Photon Irradiation

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Psychosocial Performance Factors in Space Dwelling Groups (PI Roma)

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Proteomic aided investigation of the mechanistic basis for HZE-induced cognitive impairment and the development of diagnostic biomarkers

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

The Impact of HZE Particles on Adult Neural Stem Cells and Neurogenesis

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Epigenetic Control of Radiogenic Damage Processing in C. elegans

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Individual Differences in the Neurochemical and Behavioral Response to Exposure to Protons

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-CNS - 5: How can new knowledge and data from molecular, cellular, tissue and animal models of acute CNS adverse changes or clinical human data, including altered motor and cognitive function and behavioral changes be used to estimate acute CNS risks to astronauts from GCR and SPE?

Molecular Basis of DNA Repair and Protection from Apoptosis in Neuronal Progenitors Exposed to Space Radiation

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Local CNS and Systemic Inflammatory Effects Following Proton and Mixed Particle Exposure

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Oxidative stress as a mechanism for altering acute and chronic functional changes in the CNS exposed to low dose, low dose rates, and mixed fields of protons and HZE nuclei

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Use of a molecular marker of learning and memory to assess effects of 56Fe irradiation on hippocampus-dependent cognition and neurogenesis

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Cognitive/Behavioral, Sensory, & Motor Changes Induced by Solar Particle Event (SPE) and Galactic Cosmic Ray (GCR) Irradiations

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

NSCOR: Charged Particle Radiation and Resultant Oxidative Stress Elicit Deleterious Functional Changes in the Central Nervous System

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

High LET-radiation induced DNA repair mechanisms in Oligodendrocyte progenitor cells (OPC) in vitro and in vivo

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Development and use of human 3-Dimensional tissue culture models for the study of space radiation effects on the central nervous system

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Virtual Reality (VR) Technologies for Enhancing Behavioral Health

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Behavior Tracking Software Enhancement and Integration of a Feedback Module

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Assessing Team Performance in Autonomous Environments

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Sonographic Astronaut Vertebral Examination

Common Item(s)
	Risk of Injury from Dynamic Loads

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Effects of Alphalipoic Acid on Irradiation Induced Cognitive Deficits (Postdoctoral Fellowship)

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Pharmacology Database

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Individualized Real-Time Neurocognitive Assessment Toolkit for Space Flight Fatigue

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Composing and Developing Resilient, Adaptive, and Self-Sustaining Teams for Long Duration Space Exploration

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Factors Contributing to Food Acceptability and Consumption, Mood, and Stress on Long-term Space Missions/Food Variety in Free-Living Adults

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Spaceflight Effects on Neurocognitive Performance: Extent, Longevity, and Neural Bases (NeuroMapping-Flight-Seidler)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Inadequate Human-Computer Interaction

DEFERRED: Development of an integrated sensorimotor countermeasure suite for spaceflight operations

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Developing Predictors of Sensorimotor Adaptability - ISS Flight Validation (TBD)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Effect of Sensorimotor Adaptation Following Long-Duration Spaceflight on Perception and Control of Vehicular Motion (Wood)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration
	HARI-03: We do not know how to quantify overall human-automation-robotic system performance to inform and evaluate system designs to ensure safe and efficient space mission operations. (Previous title: SHFE-HARI-03)

Evidence-based Metrics Toolkit for Measuring Safety and Efficiency in Human-Automation Systems

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration
	HARI-03: We do not know how to quantify overall human-automation-robotic system performance to inform and evaluate system designs to ensure safe and efficient space mission operations. (Previous title: SHFE-HARI-03)

Common Item(s)
	Risk of Inadequate Human-Computer Interaction
	Risk of Inadequate Mission, Process and Task Design
	MPTASK-01: We need methods and tools to collect measures of missions, process, and task performance. (Previous title: SHFE-TASK-01)

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Human Factors Analysis Support Tool (H-FAST)

Common Item(s)
	Risk of Inadequate Human-Computer Interaction

Common Item(s)
	Risk of Inadequate Mission, Process and Task Design

Common Item(s)
	Risk of Performance Errors Due to Training Deficiencies

Common Item(s)
	Risk of Performance Errors Due to Training Deficiencies

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of an Incompatible Vehicle/Habitat Design

Computational Model for Spacecraft/Habitat Volume

Common Item(s)
	Risk of an Incompatible Vehicle/Habitat Design

Electronic Procedures for Crewed Missions Beyond Low Earth Orbit (LEO)

Common Item(s)
	Risk of Inadequate Human-Computer Interaction
	Risk of Inadequate Mission, Process and Task Design

Evaluate Energy Expenditure During Long-duration (>3mo) Missions.

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Two-Hit Model of Alzheimer's Disease

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Functional decline in mice with Alzheimer's-type neurodegeneration is accelerated by charge-particle radiation

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Molecular Characterization of Long-term Degenerative CNS Risks from Space Radiation

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Identification of the Changes in the Brain Proteome Associated with HZE-induced Neurocognitive Impairment

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Multi-Modal Neurodiagnostic Tool for Stress Monitoring

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Individualized Stress Detection System

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Occupant Protection Data Mining and Modeling Project

Common Item(s)
	Risk of Injury from Dynamic Loads

Sleep Workshop

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Development and testing of biomarkers to determine individual astronauts' vulnerabilities to behavioral health disruptions

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Individualized Behavioral Health Monitoring Tool

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Objective Monitoring of Crew Neurobehavioral Functions in Mars 520-Day Simulation

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

CogGauge Enhancement

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

South Pole Station: An Analogue for Human Performance During Long Duration Missions to Isolated and Confined Environments

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Optical Computer Recognition of Stress, Affect and Fatigue in Space Flight

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Self-Guided Multimedia Stress Management and Resilience Training

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Autonomous Behavioral Health Countermeasures for Spaceflight - Virtual Space Station

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Characterize Workload on the International Space Station (ISS) (Research Requirements)

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Evidence Review: long term safety effects of low spectrum light exposure

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Effects of Space Radiation on Hippocampal-Dependent Learning and Neuropathology in Wild-Type and Alzheimer's Disease Transgenic Mice

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Effects of Space Radiation on the Function of Human Brain Capillaries and the Blood-brain-barrier: Implications for Neurodegenerative Disorders

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Molecular and Cellular Mechanisms of Space Radiation-Induced Changes in Hippocampal-Dependent Behavior

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Literature Review and Operational Assessment of Communication Strategies related to BHP

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Android App Incorporating the PVT to deliver individualized Fatigue Risk Management in Commercial Trucking

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Field test of a simple, rapid, and objective behavioral assay of group cohesion in an antarctic space analog environment

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Mitigating Neurobehavioral Vulnerabilities to Space Radiation (Postdoctoral Fellowship)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Impact of Space Radiation Induced Neuroinflammation on Alzheimer and Parkinson Disease Pathology

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Effects of high vs. Low Autonomy on Crewmember Performance in analogues

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Inflammation in the brain after particulate irradiation predisposes the hippocampus to a heightened vulnerability after a secondary insult

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Mechanisms of high LET radiation induced genomic instability in the CNS - UC Irvine Grant

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

NSCOR: Progressive Alterations of Central Nervous System Structure and Function Are Caused by Charged Particle Radiation

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Neurogenesis and cognition in human apoE transgenic mice following 56Fe radiation

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

A Scheduling and Planning Tool in NEEMO 14 – A Simulated Space Environment

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Speech monitoring of cognitive deficits and stress

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Low Dose Ionizing Radiation and HZE Particle Effects on Adult Hippocampal Neurogenesis: A Sensitive Indicator of CNS Microenvironmental Changes

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Dose-rate and mixed field effects of protons and HZE nuclei on oxidative injury and stem cell plasticity in the CNS

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Replacement Lighting for Research and Training

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Head-Eye Coordination during Simulated Orbiter Landings (Moore)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Spatial Reorientation of Sensorimotor Balance Control in Altered Gravity (Paloski)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Sensorimotor adaptation following exposure to ambiguous inertial motion cues (Wood)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Neurochemical and Behavioral Effects of Exposure to Heavy Particles -- NNJ06HD93G

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Mathematical Modeling of Circadian/Performance Countermeasures

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

A Model of Circadian Disruption in the Space Environment

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Optical Computer Recognition of Performance Under Stress

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Development of a User Interface for the PVT SelfTest (PST)

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	Sleep Gap 1: We need to identify a set of validated and minimally obtrusive tools to monitor and measure sleep-wake activity and associated performance changes for spaceflight.

Neurovestibular Aspects of Short-radius Artificial Gravity: Toward Comprehensive Counter Measure (Young)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Promoting Sensorimotor Response Generalizability: A Countermeasure to Mitigate Locomotor Dysfunction After Long-Duration Spaceflight (Bloomberg)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Data mining activities for Sensorimotor Discipline (Reschke)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Comparison of Biodynamics Models Using Automotive Racing Crash Data

Common Item(s)
	Risk of Injury from Dynamic Loads

Impact of HZE Particles Exposure on Proliferation and Differentiation of Human Neural System Cells

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

HZE Radiation Effects On Neuroinflammation: Role Of Cox-2

Common Item(s)
	Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Retrospective Analysis of Medication Usage During Long Duration Spaceflight

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Inflight pharmacokinetic and pharmacodynamic responses to medications commonly used in spaceflight

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Assessing the Impact of Communication Delay on Performance: An Examination of Autonomous Operations Utilizing the International Space Station

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Risk of Performance Errors Due to Training Deficiencies

Straight Ahead in Microgravity (Clement)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Job Analysis

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Training Needs Analysis

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Risk of Performance Errors Due to Training Deficiencies
	TRAIN-01: We do not know which validated objective measures of operator proficiency and of training effectiveness should be used for future long-duration exploration missions. (Previous title: SHFE-TRAIN-01)

Key Contributors to the Maintenance and Regulation of Team Function and Performance on Long Duration Exploration Missions

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Selection Studies Retrospective

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Psychosocial Factors Model Development (Research Requirements)

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Data mining of Benchmarking Studies (Research Requirements)

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team

Space Biochemistry Profile

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Net Habitable Volume Community of Practice

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Integrative physiology of VIIP: cardiopulmonary, sleep, and cognitive function assessment during hypercapnic bed rest [Thirty-day CO2 Bedrest/LAURIE/ACTIVE]

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Inner Ear Otoconia Response in Mice to Micro- and Hyper-gravity (Boyle)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Protocols for Asynchronous Communication in Space Operations: Communication Analysis

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Risk of Performance Errors Due to Training Deficiencies

Monitoring and Regulating Teamwork

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Development of an Objective Behavioral Assay of Cohesion to Enhance Composition, Task Performance, and Psychosocial Adaptation in Long-Term Work Groups

Common Item(s)
	Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
	Team Gap 2: We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.

Ultra-Short Light Pulses as Efficient Countermeasures for Circadian Misalignment and Objective Performance and Subjective Alertness Decrements

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

The ISS Dynamic Lighting Schedule: An in-flight lighting countermeasure to facilitate circadian adaptation, improve sleep and enhance alertness and performance on the International Space Station

Common Item(s)
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload

Automation in Procedures: Guidelines for Allocating Tasks for Performance

Common Item(s)
	Risk of Inadequate Design of Human and Automation/Robotic Integration

Markers of Susceptibility to Neurobehavioral Decrements in Space Flight

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Detection and Prevention of Neurobehavioral Vulnerability to Space Radiation II

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Bed Rest as a Spaceflight Analog to Study Neurocognitive Changes: Extent, Longevity, and Neural Bases (Seidler)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Inadequate Human-Computer Interaction

Developing Predictive Measures of Sensorimotor Adaptability to Produce Customized Countermeasure Prescriptions (Bloomberg)

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	Risk of Inadequate Human-Computer Interaction

Multi-Use Near-Infrared Spectroscopy System for Spaceflight Health Applications

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
	CBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.

Potential Subclinical Neurologic Changes in Astronauts due to Repeated Hypobaric Exposures

Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

Common Item(s)
	Risk of Injury from Dynamic Loads

Deconditioning Summit

Common Item(s)

Ground-Based Flight Analogs Controlled Research Analog, Short Duration (2 months or less) – isolated and confined with spaceflight mission scenario [e.g., HERA, NEEMO]
Number of Subjects	32