Last Published:  07/30/20 02:45:15 PM (Central)
Short Title: GSAM
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
Directed
Aims:

GSAM project provides delivery scheme of low and high LET particles to best simulate 600/900 day Mars missions within facility and animal constraints.

  • Studies required to inform countermeasure testing and validation
  • Fluence based versus acute exposures to simulate space radiation 

 

GSAM (GCR Simulation and Mitigation) research objectives:

 

Aim 1:  Design and implement Hybrid Shield Concept to simulate GCR environment at NSRL to include production of secondaries and correlated multiplicities found in space

Aim 2:  Validate ground simulation of dose rate including fractionation and time course delivery of particles to simulate low dose chronic exposures in space.  

Aim 3: Evaluation of dose delivery scheme with biological timescales to inform chronic studies.

Aim 4: Expand design and implement Mars surface simulation at NSRL to include mixed field environment found on Mars surface.


Resources (None Listed)
Mappings
RiskRisk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
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RiskRisk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
GapBMed-103: What are the validated, efficacious treatments (individual or Team-based) and/or countermeasures to prevent adverse behavioral conditions, CNS/neurological, and/or psychiatric disorders caused by either single and/or integrated exposures to spaceflight hazards during exploration class missions?
GapBMed-104: Given the potentially negative spaceflight associated CNS changes and behavioral experiences of stressors during long-duration missions (e.g., isolation, confinement, reduced sensory stimulation, altered gravity, space radiation), what are validated modifications to habitat/vehicle to mitigate stressors impacting on CNS / cognition / behavioral health?
GapBMed-105: Given the potentially negative spaceflight associated CNS/cognitive changes and behavioral experiences of stressors during long-duration missions (e.g., isolation, confinement, reduced sensory stimulation, altered gravity, space radiation), what are validated medical or dietary countermeasures to mitigate stressors impacting on CNS / cognition / behavioral health?
GapBMed-107: What are the long-term changes and risks to astronaut health post-mission that, when using a continuity of care model, helps retrospectively identify and understand individual susceptibility (e.g., hereditary, dose, thresholds) to mitigate adverse CNS, cognitive, and behavioral health changes resulting from long-duration exploration missions, promoting the behavioral health of current and future crews?
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RiskRisk of Cardiovascular Disease and Other Degenerative Tissue Effects From Radiation Exposure and Secondary Spaceflight Stressors
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RiskRisk of Radiation Carcinogenesis
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RiskRisk of Spaceflight Induced Cardiovascular Disease
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