Short Title:
CBS RR: NHP Model Brain Performance Pathways
Responsible HRP Element:
Human Factors and Behavioral Performance
Collaborating Org(s):
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Human Health Countermeasures (HHC) Element |
Space Radiation (SR) Element |
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Funding Status:
Planned-Unfunded - Task not within current budget
Procurement Mechanism(s):
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Aims:
The conceptualization of Brain Performance Pathways (BPP) is based on how the architecture of brain networks at rest guide the connectivity patterns that emerge during the performance of various tasks (i.e., modularity measured during "resting states" predicts working memory performance and stimulus detection in a perceptual task). Past CNS research focuses on single ions and dosages, identifying differential sensitivity of brain tissue that is more likely to disrupt modular brain organization (i.e., Brain Performance Pathways).
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
-Report on NHP Brain Performance Pathways and connectivity patterns observed in past research (radiation, stress, SM).
-Identify NHP models for operationally-relevant brain performance pathways conceptualized within the CBS Integrated research plan.
-Findings addressed within context of spaceflight relevant dose-effects and synergistic effects of CBS risks.
Internal Customers:
Human Factors and Behavioral Performance
Human Health Countermeasures
Space Radiation
External Customers:
None