Task Future research (NSCOR) -- potential topics include RBEs, Glial cell response, stress response, cross-species homology, animal mood/social/cognition, sleep/stress/cognition, neural plasticity, dose rate effect for multiple measures
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: CBS NSCOR #1: Single Beam GCRsim Mixed Field
Responsible HRP Element: Human Factors and Behavioral Performance
Collaborating Org(s):
Human Health Countermeasures (HHC) Element
Space Radiation (SR) Element
Funding Status: Planned-Funded - Task expected to be within budget
Procurement Mechanism(s):
Solicited
Aims:
Large-scale research study to assess integrated CBS risk by incorporating needed topics such as radiation biological effects (RBEs), Glial cell responding, stress response, cross-species homology, animal mood/social/cognition, sleep/stress/cognition, neural plasticity, dose rate effect for multiple measures related to CBS risk.
Resources (None Listed)
Mappings
RiskRisk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
GapBMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
GapBMed-103: What are the validated, efficacious treatments (individual or Team-based) and/or countermeasures to prevent adverse behavioral conditions, CNS/neurological, and/or psychiatric disorders caused by either single and/or integrated exposures to spaceflight hazards during exploration class missions?
GapBMed-107: What are the long-term changes and risks to astronaut health post-mission that, when using a continuity of care model, helps retrospectively identify and understand individual susceptibility (e.g., hereditary, dose, thresholds) to mitigate adverse CNS, cognitive, and behavioral health changes resulting from long-duration exploration missions, promoting the behavioral health of current and future crews?
GapBMed-108: Given each crewmember will experience multiple spaceflight hazards simultaneously, we need to identify and characterize the potential additive, antagonistic, or synergistic impacts of multiple stressors (e.g., space radiation, altered gravity, isolation, altered immune, altered sleep) on crew health and/or CNS/ cognitive functioning to develop threshold limits and validate countermeasures for any identified adverse crew health and/or operationally-relevant performance outcomes.
You are here!TaskFuture research (NSCOR) -- potential topics include RBEs, Glial cell response, stress response, cross-species homology, animal mood/social/cognition, sleep/stress/cognition, neural plasticity, dose rate effect for multiple measures

RiskRisk of Impaired Control of Spacecraft/Associated Systems and Decreased Mobility Due to Vestibular/Sensorimotor Alterations Associated with Spaceflight
You are here!TaskFuture research (NSCOR) -- potential topics include RBEs, Glial cell response, stress response, cross-species homology, animal mood/social/cognition, sleep/stress/cognition, neural plasticity, dose rate effect for multiple measures