Task Investigating Structure and Function of the Eye - ISS (Macias)
Last Published:  07/30/21 01:05:34 PM (Central)
Short Title: CIPHER iSAFE
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
Solicited
Aims:

This proposal will identify if ocular structure and function alterations occur at a greater frequency and magnitude during one-year missions compared to six-month and six-week expeditions and whether the recovery profile is dependent upon mission duration. In addition, this project will determine if changes in vascular structure and function are greater after one-year missions and contribute to alterations in ocular structure and function. The identification of structural and functional changes will provide NASA the information necessary to inform the risk posture for future interplanetary expeditions with durations of up to three years and to identify possible countermeasures.



Aims:

  1. Determine if ocular structural and functional changes develop to a greater degree (frequency or magnitude) during 1-year missions compared to shorter and if recovery is prolonged

  2. Determine if ocular vascular structure and function is altered to a greater degree during 1YMs, and if recovery is more prolonged

  3. Determine if ocular functional changes develop to a greater degree (frequency or magnitude) during 1-year missions compared to shorter and if recovery is prolonged

  4. Determine if the vascular adaptations correlate with alterations in ocular structure and function.

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