HRR - Task - Can behavioural countermeasures module the risk of stress-induced altered immunity and latent herpesvirus shedding in college students

NASA Logo Human Research Roadmap HRP Exploration Data

{1}

##LOC[OK]##

{1}

##LOC[OK]## ##LOC[Cancel]##

{1}

##LOC[OK]## ##LOC[Cancel]##

Evidence Risks Gaps Tasks Reports

Explore Search

- IM-403
  - Immune

Can behavioural countermeasures module the risk of stress-induced altered immunity and latent herpesvirus shedding in college students

Last Published: 11/23/20 11:55:12 AM (Central)

Task Book: Entry Unavailable
Principal Investigator: TBD

Short Title: VGSC support

Responsible HRP Element: Human Health Countermeasures

Collaborating Org(s):

Funding Status: Active - Currently funded and in progress

Procurement Mechanism(s):

Directed

Aims:
SA 1 : Investigate the effect if academic stress on cytokine profiles and other relevant immune/stress biomarkers

SA 2 : Investigate the effect of academic stress on the reactivation and shedding of latent herpesviruses

SA 3: Characterize the other positive effect of the behavioral countermeasure on mitigating the immune dysregulation associated with academic stress.

Resources (Other)

Other Resources

Other Resources Needed?

Yes

Deliverables (1)

Category: Study Results
Subcategory:

Description:
Flight data will be collected for all proposed assays

Internal Customers:
None External Customers:
None

Mappings

Risk of Adverse Health Event Due to Altered Immune Response

IM-403: Test, optimize and validate stress reduction techniques as preventive and mitigative immune dysfunction countermeasures.

Can behavioural countermeasures module the risk of stress-induced altered immunity and latent herpesvirus shedding in college students

Related Tasks (44)

Nutritional Status Assessment: SMO-016E

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The impact of modeled microgravity and prior radiation exposure on cytomegalovirus reactivation and host immune evasion

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Microbial Risk Assessment and Integration

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Immune Countermeasures Validation (Analog)

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response
	IM-403: Test, optimize and validate stress reduction techniques as preventive and mitigative immune dysfunction countermeasures.

Validation of Procedures for Monitoring Crewmember Immune Function (Integrated Immune - SMO 015/SDBI 1900) Completed

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Flight-Induced Changes in Immune Defenses-DSO 498

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Incidence of Latent Virus Shedding During Space Flight-DSO 493

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Space Flight-Induced Reactivation of Latent Epstein-Barr Virus

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Consequences of Long-term Confinement and Hypobaric Hypoxia on Immunity in the Antarctic Concordia Environment (CHOICE)

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The Effects of Long-Term Exposure to Microgravity on Salivary Markers of Innate Immunity

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Immune Countermeasures Validation - Flight

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response
	IM-403: Test, optimize and validate stress reduction techniques as preventive and mitigative immune dysfunction countermeasures.

Examination of Splenic and Thymic Immune Function in Mice (STS-135 Mouse Tissue Sharing Pilot Study)

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Evaluation of the combined effects of gamma radiation and high dietary iron on oxidative damage and antioxidant status in rats (Immune Assessment)

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Evaluation of Host-Pathogen Interactions During Exposure to Microgravity Analogues -- ASU Grant

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Clinical Immunology Study - European Collaboration

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Space Biochemistry Profile

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Integrative physiology of VIIP: cardiopulmonary, sleep, and cognitive function assessment during hypercapnic bed rest [Thirty-day CO2 Bedrest/LAURIE/ACTIVE]

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Functional immune alterations, latent Herpesvirus reactivation, physiological stress and clinical incidence onboard the International Space Station

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Immune Clinical Correlations

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Monitoring the Cellular Immunity by in vitro Delayed Type Hypersensitivity Assay on ISS

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Deep Space Exploration Atmosphere Effects on Hematologic, Immunologic, and Oxidative Stress and Damage Parameters in Astronauts: An ISS Flight Study

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Consequences of longterm-confinement and hypobaric hypoxia on immunity in the Antarctic Concordia Environment: from observations to mechanisms

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The Integrated Impact of Diet on Human Immune Response, the Gut Microbiota, and Nutritional Status During Adaptation to Spaceflight

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Effects of space flights on the proteome of astronauts' plasma (Rithidech) functional immune

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

DNA damage in the ISS astronaut's lymphocytes and their association with stress-induced immune dysfunction (Honglu Wu) Functional immune

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The impact of an ISS mission on the anti-viral and functional properties of NK-cells, T-cells, B-cells and dendritic cells (Simpson) Functional immune

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The impact of long duration spaceflight on the function of B-cells and biomarkers of inflammation (Spielmann)

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Assessment of Normoxic Coastal Antarctic Winterover as an Analog for Spaceflight Immune Dysregulation

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Spaceflight-Induced Changes in Microbial Virulence and the Impact to the Host Immune Response

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Immune Countermeasure

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response
	IM-403: Test, optimize and validate stress reduction techniques as preventive and mitigative immune dysfunction countermeasures.

CBS VNSCOR #1: Responses of the Nervous System to Chronic, Low Dose Charged Particle Irradiation

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Pilot Assessment of Stress and Latent Herpesvirus Reactivation at Palmer, Antarctica - Platform for Validation of Immune Countermeasures?

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Varicella Zoster virus shedding after antiviral drug (Valacyclovir) treatment in Antarctic expeditioners

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Exploration Atmosphere Bedrest

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Characterizing the Baselines of Sleep Quality, Cognitive / Operational Performance, Immune Function, and Intracranial Fluids for Deep Space Expeditions

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

MinION Viral Detection

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Awakening endogenous retroviruses with the space environment

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Cardiovascular responses to simulated spaceflight: molecular signatures and surrogate outputs to measure CVD risk.

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The impact of human spaceflight on clonal hematopoiesis

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Endogenous Retrovirus Activation

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Conditions of Toll like receptors system of the human innate immunity cells during long-term isolations

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Pre-in-post Saliva/blood/urine Gateway (Flight)

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The impact of simulated microgravity on the anti-tumor properties of human NK-cells and ?d-T cells in vivo: IL-2 and zoledronic acid therapy as a potential countermeasure

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

The Integrated Impact of Diet on Human Immune Response, the Gut Microbiota, and Nutritional Status During Adaptation to Spaceflight 2 (HRP Funded)

Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response

Print View...

PRRs (1)

This task can be found in the following Paths to Risk Reduction.

Immune Path to Risk Reduction

{1}

##LOC[OK]##

{1}

##LOC[OK]## ##LOC[Cancel]##

{1}

##LOC[OK]## ##LOC[Cancel]##

NASA Developer: Daniel Febus Responsible NASA Official: Susan Torney Contact HRP for a 508 compliant PDF Budgets, Strategic Plans, and Accountability Reports Equal Employment Opportunity Data Posted Pursuant to the No Fear Act Information-Dissemination Policies and Inventories Freedom of Information Act President's Management Agenda Privacy Policy & Important Notices Inspector General Hotline Contact HRP Human Health and Performance DIR Johnson Space Center USA.gov ExpectMore.gov