Task Potential Role of the Endothelium in Internal Jugular Venous Thrombosis due to Abnormal Venous Flow Patterns During Spaceflight (Taylor)
Last Published:  03/26/21 03:34:00 PM (Central)
Short Title: IJV Endothelium Role-Rodent
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
Solicited
Aims:

Aim I: Recapitulate the Abnormal IJV flow patterns observed in crew members
aboard the ISS in an isolated, perfused vein organ culture system and determine if
there are changes in endothelial gene expression using RNA sequencing.

Aim II: Confirm that any changes in candidate genes identified in Aim I are
expressed at the protein level.


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