Task Establishing the impact of sleep disruptions on neural network connectivity when under cognitive loading
Last Published:  04/20/22 11:43:24 AM (Central)
Short Title: CBS Sleep Disruptions on Neural Network Connectivity (Britten)
Responsible HRP Element: Human Factors and Behavioral Performance
Collaborating Org(s):
Human Factors and Behavioral Performance (HFBP) Element
Human Health Countermeasures (HHC) Element
Space Radiation (SR) Element
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):


Aim 1: Establish the impact that 3 examples of SF have on neural network coherence while rats are performing under cognitive load (Konnect task):

  1. Acute Mild SF (published protocol, sleep interrupted every 2 mins for 1 sleep period prior to testing),

  2. Chronic Mild SF (3 sleep periods of sleep interrupted every 2 mins prior to testing),

  3. Pre-EVA sleep simulation (reduction of sleep period by 5.5 hours followed by 6.5 hours of SF every 2 mins during sleep period prior to testing).

    15 rats per treatment group will be studied.

Aim 2: Establishing the impact that three SF protocols have on sleep spindle activity, and whether there is any correlation to either the loss of network coherence or Konnect performance.

Aim 3: Mine the data from Aims1 and 2 to identify LFP/network coherence/sleep spindle signatures that identify sleep sensitive or tolerant individuals with regards to cognitive performance.

Resources (None Listed)