Task Vitamin D Supplement Evaluation of Dosing Requirements (Completed)
Last Published:  03/26/21 03:34:00 PM (Central)
Short Title: Vitamin D Dosing
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Directed
Aims:
  1. Determine the time course and magnitude of changes in vitamin D and vitamin D metabolite status with each dose of vitamin D supplementation.  We will also determine markers of calcium and liver enzyme status to document potential side effects.
  2. Determine other markers of bone and calcium metabolism (including serum and urinary calcium, bone-specific alkaline phosphatase, 1,25-dihydroxyvitamin D, parathyroid hormone, and vitamin D binding protein) and vitamin D metabolites over a 4-month course of vitamin D supplementation, to determine the effectiveness and safety of each level of supplementation.

Integration/Unique Aspects: TBD

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