Task Characterization of Oxidative Damage During a Saturation Dive (Completed)
Last Published:  07/31/19 10:05:33 AM (Central)
Short Title: NEEMO XIV Nutrition ROI
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Other:
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Directed
Aims:
  1. To expand measurements of oxidative damage to include more markers to better characterize the type of damage.  Some examples include gammmaH2AX and HMGB1, which are early event markers for tissue injury and inflammation and have broad application.
  2. To measure markers of hemolysis (haptoglobin and hemopexin) to better understand the increase in iron storage during NEEMO missions.
  3. To measure markers of folate status to better understand the effect of an oxidative stress on folate metabolism.


Integration/Unique Aspects: TBD

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