Short Title:
Integrative CM
Responsible HRP Element:
Human Health Countermeasures
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Collaborating Org(s):
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| National Space Biomedical Research Institute (NSBRI) |
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Funding Status:
Completed - Task completed and produced a deliverable
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Procurement Mechanism(s):
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Aims:
Test an integrated countermeasure that will be effective against cardiovascular deconditioning, skeletal muscle atrophy, and bone demineralization, and that ultimately can be applied practically abroad the International Space Station or a mission to Mars.
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
Provide information that will assist in the development of an integrated countermeasure for cardiovascular deconditioning.
PI Publications (excerpt)
Fu Q, VanGundy TB, Galbreath MM, Shibata S, Jain M, Hastings JL, Bhella PS, Levine BD. "Cardiac origins of the postural orthostatic tachycardia syndrome." J Am Coll Cardiol. 2010 Jun 22;55(25):2858-68.
Otto C, Hamilton DR, Levine BD, Hare C, Sargsyan AE, Altshuler P, Dulchavsky SA. "Into thin air: extreme ultrasound on Mt Everest." Wilderness Environ Med. 2009 Fall;20(3):283-9.
Shibata S, Perhonen M, Levine BD. "Supine cycling plus volume loading prevent cardiovascular deconditioning during bed rest." J Appl Physiol. 2010 May;108(5):1177-86.
Wood HE, Levine BD, Babb TG. "Ventilatory responses to exercise and hypercapnia following 18 days of head-down rest." Aviat Space Environ Med. 2009 Apr;80(4):395-9.
Internal Customers:
Human Health Countermeasures
External Customers:
None