HRR - Task - Microbial Risk Assessment and Integration

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Microbial Risk Assessment and Integration (Completed)

Last Published: 11/23/20 11:55:12 AM (Central)

Task Book: Entry
Principal Investigator: Ott, C. Mark

Short Title: Microbial Risk

Responsible HRP Element: Space Human Factors and Habitability

Collaborating Org(s):

Funding Status: Completed - Task completed and produced a deliverable

Procurement Mechanism(s):

Directed

Aims:

This task used quantitative microbial risk assessment approaches that have been applied to great success in the food and potable water industries data sets obtained in space travel. Findings are the basis for the development of a systematic approach that will reduce health risks to crews while at the same time reducing costs by optimizing allocation of resources.

Consolidated and integrated results of studies and modeling to support the development and incorporation of infectious disease risk data into operational processes.

Provided data that will support solicited studies that address risks associated with Host-Microbe interactions.

Resources (Other)

Deliverables (1)

Category: Requirement
Subcategory: Guidelines/Criteria

Description:
Deliverables include a microbial risk model for quantitative assessment of infectious disease, and recommendations for operational processes and constraints to minimize exposure to microbial contaminants. This is a continuing effort that will integrate new results into the risk model as information and data become available.

Internal Customers:
Space Human Factors and Habitability
External Customers:
Office of the Chief Health and Medical Officer (OCHMO)

Is a Customer-Supplier Agreement (CSA) Required? No

Mappings

Risk of Adverse Health Effects Due to Host-Microorganism Interactions

Micro-202: Evaluate the contribution of changes in microbial numbers, types, and virulence on the likelihood and consequence of non-infection-based effects on health and performance, including: decrease in cognition/mood/performance/blood-brain barrier (BBB) function related to the change in the gut’s microbiome and gut-brain axis, increase in cardiovascular health risks, effects of change in gut microbiome on metabolism of nutrients, and correlation with inflammation.

Micro-401: Test, optimize and validate existing terrestrial or novel technologies that can maintain in-flight microbial counts, types, and virulence at terrestrial equivalent levels.

Microbial Risk Assessment and Integration

Risk of Adverse Health Event Due to Altered Immune Response

IM-101: Evaluate the effects of deep-space radiation on immune dysfunction, as an additional hazard to the effects of psychophysiological stress and weightlessness.

Microbial Risk Assessment and Integration

Related Tasks (70)

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PRRs (2)

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Common Item(s)
	Risk of Adverse Health Event Due to Altered Immune Response
	IM-101: Evaluate the effects of deep-space radiation on immune dysfunction, as an additional hazard to the effects of psychophysiological stress and weightlessness.