Task Validation of Procedures for Monitoring Crewmember Immune Function (Integrated Immune - SMO 015/SDBI 1900) Completed (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: Integrated Immune
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):

There are no procedures currently in place to monitor immune function or its effect on crew health.  Immune dysregulation has been demonstrated to occur during spaceflight, yet little in-flight immune data has been generated to assess whether or not this may be a clinical problem.  This SMO will assess the clinical risks resulting from the adverse effects of space flight on the human immune system and will validate a flight-compatible immune monitoring strategy.  The correlation between in-flight immunity, physiological stress and a measurable clinical outcome (viral reactivation) will be determined for long- vs. short-duration space flight.

  1. The objective of this Supplemental Medical Objective (SMO) is  1) to develop and validate an immune monitoring strategy consistent with operational flight requirements and constraints.

Integration/Unique Aspects: Supports AEH 14