Short Title:
Immune Function
Responsible HRP Element:
Human Health Countermeasures
Funding Status:
Completed - Task completed and produced a deliverable
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Procurement Mechanism(s):
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Aims:
Shuttle-based study investigating the effects of space flight on 1) neutrophil and monocyte functions (phagocytosis, degranulation, oxidative burst capacity, and expression of surface molecules) and 2) natural-killer cell and lymphokine-activated killer cell cytotoxicity against target cells, and cytokine production.
Integration/Unique Aspects: TBD
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
This task contributes to the closure of IM1 by addressing the gaps first interim step of obtaining baseline data characterizing adaptive immunity. This task contributes to the closure of IM2 by addressing the gaps first interim metric of providing incremental characterization of the in-flight human immune system. Results have produced multiple publications citations can be found in the NASA taskbook .
Internal Customers:
None
External Customers:
None