Short Title:
Fracture Healing
Responsible HRP Element:
Human Health Countermeasures
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Collaborating Org(s):
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| National Space Biomedical Research Institute (NSBRI) |
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Funding Status:
Completed - Task completed and produced a deliverable
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Procurement Mechanism(s):
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Aims:
- Determine the scope and extent of femoral fracture healing impairment
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Determine the underlying biological causes of the impairment
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Develop countermeasures to prevent fracture healing impairment
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Determine whether current Earth-based clinical procedures will reverse severely delayed fracture healing situations resulting from hypogravity.
Integration/Unique Aspects: This task is shared with ExMC by sharing information/data generated HHC investigations of bone strength and biomechanical loads.
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
This Task generated evidence on fracture healing impairment in a small animal model.
This Task contributed to Fracture 1 closure by characterizing healing, at the tissue and cellular level, in a mechanically-unloaded rodent model.
Internal Customers:
None
External Customers:
None