Task Role of high-LET radiation-induced mitotic catastrophe in mutagenesis: implication for carcinogenesis (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: Mitotic catastrophe
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
This Project aims at testing the hypotheses that iron and proton ions induce genetic imbalances in exposed human cells via processes occurring in cells that undergo radiation-induced mitotic catastrophe (MC) (reviewed in Ianzini and Mackey 2007) and that this induced instability correlates with increased cancer risk.
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