Task DNA Damage Clusters in Human Cell Transformation Induced by Single or Multiple Space Radiation Ion Exposures--Wilson (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: DNA Damage Cluster
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
We are initiating studies to determine whether levels of slowly-repaired or unrepaired, persistent clusters correlate with the human cell neoplastic transformation frequencies observed with mixed field radiations. We are determining whether conditions or agents that reduce the levels or types of endogenous or radiation-induced clusters also reduce transformation levels, thus suggesting approaches to mitigation of cancer risk during space travel
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