Task Elucidating the Relationship Between the Effects of Various Radiation Qualities and Cancer Development Processes using Novel Flow-based Assays (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: Novel Flow
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
In this proposal we will study critical phosphorylation signaling at early and late time points as well as surrogate cancer endpoints of telomere length changes and genomic stability as measured by centrosome amplification, at these same late times post exposure. Epithelial and fibroblast cells from the same individuals will be used to better understand the etiology of cancer, and why certain cell types more easily become carcinogenic. We will also perform studies to understand the heterogeneous nature of high LET radiation.
Resources (None Listed)
Mappings
RiskRisk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
You are here!TaskElucidating the Relationship Between the Effects of Various Radiation Qualities and Cancer Development Processes using Novel Flow-based Assays

RiskRisk of Cardiovascular Disease and Other Degenerative Tissue Effects From Radiation Exposure and Secondary Spaceflight Stressors
You are here!TaskElucidating the Relationship Between the Effects of Various Radiation Qualities and Cancer Development Processes using Novel Flow-based Assays

RiskRisk of Radiation Carcinogenesis
You are here!TaskElucidating the Relationship Between the Effects of Various Radiation Qualities and Cancer Development Processes using Novel Flow-based Assays