HRR - Task - A mechanistic investigation of space radiation-induced carcinogenesis

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A mechanistic investigation of space radiation-induced carcinogenesis - NNX12AB88G (Completed)

Last Published: 04/20/22 11:43:24 AM (Central)

Task Book: Entry
Principal Investigator: Li, Chuan-Yuan

Short Title: SR Carcinogenesis

Responsible HRP Element: Space Radiation

Collaborating Org(s):

Funding Status: Completed - Task completed and produced a deliverable

Procurement Mechanism(s):

Solicited

Aims:

To determine the potential interactions of reactive oxygen/nitrogen species and apoptosis in regulating HZE radiation-induced mutagenesis in mammalian cells.
To determine the roles of program cell death in HZE radiation induced mutagenesis/carcinogenesis.

Resources (None Listed)

Deliverables (1)

Category: Risk Characterization, Quantification
Subcategory: Evidence or Risk Characterization

Description:
Annual and Final Reports

Internal Customers:
Space Radiation
External Customers:
None

Mappings

Risk of Radiation Carcinogenesis

Cancer-202: Evaluate the contribution of genetic background/diversity on carcinogenesis risk.

A mechanistic investigation of space radiation-induced carcinogenesis - NNX12AB88G

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Risk Approach Plans (1)

This task can be found in the following Risk Approach Plans.

Cancer Risk Approach plan

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