Task Radiation and Gliomagenesis: A Sensitive Model System to Evaluate the Tumorigenic Potential of HZE Particles (Completed)
Last Published:  03/26/21 03:34:00 PM (Central)
Short Title: HZE Gliomagenesis
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):

Aim 1: Evaluation of DNA damage responses to charged particles in neural stem cells (NSCs) and astrocytes in vitro and in vivo.

Aim 2: Evaluation of the tumorigenic potential of charged particles relative to gamma rays in vitro and in vivo.

Aim 3: Identification of the genetic and gene expression changes underlying particle-induced tumorigenesis.

Resources (None Listed)