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BMed-102
BMed
CBS-BMed2
BMed
Optical Computer Recognition of Stress, Affect and Fatigue During Performance in Spaceflight
(Completed)
Last Published:
03/26/21 03:34:00 PM (Central)
Task Book:
Entry
Principal Investigator:
Dinges, David
Short Title:
OCR Spaceflight
Responsible HRP Element:
Behavioral Health and Performance
Collaborating Org(s):
National Space Biomedical Research Institute (NSBRI)
Funding Status:
Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
Create an OCR system capable of monitoring facial displays of specific emotions (i.e. angry, happy and sad).
Improve our current OCR system's ability to detect facial expressions of high versus low performance-induced stress.
Develop OCR algorithms to identify fatigue due to sleep loss based on slow eyelid closures (PERCLOS).
Test the technical feasibility of data acquisition and reliability of the advanced OCR system in spaceflight analogs that contain neurobehavioral stressors relevant to spaceflight (e.g., NEEMO).
Resources
(
None Listed
)
Deliverables (
1
)
Category:
Technology or Tool
Subcategory:
Computational Models or Simulations
Description:
Prototype software TRL4/5 {requiring further refinement and validation before it can become operational in spaceflight environment}
Internal Customers:
Behavioral Health and Performance
External Customers:
Med Ops - Medical Operations
Is a Customer-Supplier Agreement (CSA) Required?
Yes
Mappings
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Optical Computer Recognition of Stress, Affect and Fatigue During Performance in Spaceflight
Related Tasks (271)
Space Radiation Risk Assessment Project-Cucinotta
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Sensory Stimulation Augmentation Tools (RR)
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Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Hybrid Training - A Sensory Stimulation Countermeasure for Long Duration Space Exploration Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Psychomotor Vigilance Test (PVT) on ISS
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Promoting behavioral health, cognitive, sensorimotor and immune function using guided imagery to augment exercise training in an isolated and confined spaceflight analog environment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Objective Detection, Evaluation and Countermeasures for In-flight Depression
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Objective Monitoring of Crew Neurobehavioral Functions (105-day Russian Chamber Study)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Neurobehavioral Conditions List for Exploration Missions (RR)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Asthenia Literature Review
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Voice Content Analysis Techwatch
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Detection & Prevention of Neurobehavioral Vulnerability to Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Evidence Review: Cognition in Long Duration Missions in Isolated, Confined and Extreme Environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Validation of Assessment Tests and Countermeasures for Detecting and Mitigating Changes in Cognitive Function During Robotics Operations
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Integrated Cognitive Assessment: Combining Measurement, System, and Mission
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Neurostructural, Cognitive, and Physiologic Changes During a 1-year Antarctic Winter-Over Mission
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
The Prediction of the Onset of Anxiety Disorders
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
White Paper on the Onset of Depression
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Meta-Analysis of the effects of ICE environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Evidence Review on Identification of Psychosocial Characteristics in ICE Environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Growth and Resilience for Long Duration Exploration Missions(RR)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Effects of Well-Being on Performance in ICE Environments (RR)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Individual differences and adaptation to Isolated, Confined, and Extreme (ICE) environments (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Self-Guided Depression Treatment on Long-Duration Spaceflights
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
A Multi-Media, Computer-Based, Self-Directed, Autonomous, Stress and Anxiety-Management Countermeasure
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Behavioral Issues Associated with Long Duration Space Missions: Review of Astronaut Journals
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Asynchronous Behavioral Health Treatment Techniques
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Immune Function Data Mining
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Sleep-Wake Actigraphy and Light Exposure During Spaceflight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Environmental Factors Evidence Review
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
The Biological Basis of Emotional Support for Long Duration Exploration Missions (RR)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Determine best methods to maintain contact with astronaut social support network during pre-mission training (RR)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Evidence Review on Biomarkers of Individual Vulnerabilities to Sleep Loss and Circadian Desynchronization
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
AD ASTRA: Automated Detection of Attitudes and States through Transaction Recordings Analysis
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Team Risk Standardized Measures Workshop
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Operational Evaluation of Photic Countermeasure to Improve Alertness, Performance, and Mood during Nightshift Work on a 105-Day Study (105-day Russian Chamber Study)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Countermeasure for Managing Interpersonal Conflicts in Space: A Continuation Study
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
ANSIBLE: A Network of Social Interactions for Bilateral Life Enhancement
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Dynamic Team Role Allocation in Long Duration, Exploration Missions: Identification of Roles, Triggers, and Measurement Tools
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Optimizing Light for Long Duration Space Exploration
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Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Blue Light for Enhancing Alertness in Space Missions
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Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Feasibility Pilot Study on Acute Biological and Behavioral Responses to the Solid State Lighting Modules for the International Space Station
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Testing solid state lighting countermeasures to improve circadian adaptation, sleep, and performance during high fidelity analog and flight studies for the International Space Station
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Develop and Implement Operational Ground Testing Protocols to Individualize Astronaut Sleep Medication Efficacy and Individual Effects (pilot study)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Operational Ground Testing Protocols to Individualize Astronaut Sleep Medication Efficacy and Individual Effects
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Designing Individual Countermeasures to Reduce Sleep Disruption and Improve Performance and Alertness in Space
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Countermeasures for Performance Deficits from Sleep Loss and Workload in Space Flight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Individualized Fatigue Meter for Space Exploration (SBIR Phase II)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Survey of On-Orbit Sleep Quality (Sleep Quality Questionnaire)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Phoenix Scout Lander: Countermeasures Testbed for Spaceflight Ground Controllers
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
A Comprehensive Fatigue Management Program and an Evaluation of a Photic Countermeasure for Mission Controllers
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Neurodegeneration and Adaptation in Response to Low-Dose Photon Irradiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Proteomic aided investigation of the mechanistic basis for HZE-induced cognitive impairment and the development of diagnostic biomarkers
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
The Impact of HZE Particles on Adult Neural Stem Cells and Neurogenesis
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Epigenetic Control of Radiogenic Damage Processing in C. elegans
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Individual Differences in the Neurochemical and Behavioral Response to Exposure to Protons
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Molecular Basis of DNA Repair and Protection from Apoptosis in Neuronal Progenitors Exposed to Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Local CNS and Systemic Inflammatory Effects Following Proton and Mixed Particle Exposure
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Oxidative stress as a mechanism for altering acute and chronic functional changes in the CNS exposed to low dose, low dose rates, and mixed fields of protons and HZE nuclei
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Use of a molecular marker of learning and memory to assess effects of 56Fe irradiation on hippocampus-dependent cognition and neurogenesis
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Cognitive/Behavioral, Sensory, & Motor Changes Induced by Solar Particle Event (SPE) and Galactic Cosmic Ray (GCR) Irradiations
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
NSCOR: Charged Particle Radiation and Resultant Oxidative Stress Elicit Deleterious Functional Changes in the Central Nervous System
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
High LET-radiation induced DNA repair mechanisms in Oligodendrocyte progenitor cells (OPC) in vitro and in vivo
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Development and use of human 3-Dimensional tissue culture models for the study of space radiation effects on the central nervous system
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Virtual Reality (VR) Technologies for Enhancing Behavioral Health
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Assessing Team Performance in Autonomous Environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Effects of Alphalipoic Acid on Irradiation Induced Cognitive Deficits (Postdoctoral Fellowship)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Individualized Real-Time Neurocognitive Assessment Toolkit for Space Flight Fatigue
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Composing and Developing Resilient, Adaptive, and Self-Sustaining Teams for Long Duration Space Exploration
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Two-Hit Model of Alzheimer's Disease
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Functional decline in mice with Alzheimer's-type neurodegeneration is accelerated by charge-particle radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Molecular Characterization of Long-term Degenerative CNS Risks from Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Identification of the Changes in the Brain Proteome Associated with HZE-induced Neurocognitive Impairment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Multi-Modal Neurodiagnostic Tool for Stress Monitoring
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Sleep Workshop
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Development and testing of biomarkers to determine individual astronauts' vulnerabilities to behavioral health disruptions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Individualized Behavioral Health Monitoring Tool
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Objective Monitoring of Crew Neurobehavioral Functions in Mars 520-Day Simulation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CogGauge Enhancement
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
South Pole Station: An Analogue for Human Performance During Long Duration Missions to Isolated and Confined Environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Optical Computer Recognition of Stress, Affect and Fatigue in Space Flight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Self-Guided Multimedia Stress Management and Resilience Training
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Autonomous Behavioral Health Countermeasures for Spaceflight - Virtual Space Station
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Characterize Workload on the International Space Station (ISS) (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Effects of Space Radiation on Hippocampal-Dependent Learning and Neuropathology in Wild-Type and Alzheimer's Disease Transgenic Mice
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Effects of Space Radiation on the Function of Human Brain Capillaries and the Blood-brain-barrier: Implications for Neurodegenerative Disorders
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Molecular and Cellular Mechanisms of Space Radiation-Induced Changes in Hippocampal-Dependent Behavior
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Android App Incorporating the PVT to deliver individualized Fatigue Risk Management in Commercial Trucking
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Mitigating Neurobehavioral Vulnerabilities to Space Radiation (Postdoctoral Fellowship)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Impact of Space Radiation Induced Neuroinflammation on Alzheimer and Parkinson Disease Pathology
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Inflammation in the brain after particulate irradiation predisposes the hippocampus to a heightened vulnerability after a secondary insult
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Mechanisms of high LET radiation induced genomic instability in the CNS - UC Irvine Grant
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
NSCOR: Progressive Alterations of Central Nervous System Structure and Function Are Caused by Charged Particle Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Neurogenesis and cognition in human apoE transgenic mice following 56Fe radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Speech monitoring of cognitive deficits and stress
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Low Dose Ionizing Radiation and HZE Particle Effects on Adult Hippocampal Neurogenesis: A Sensitive Indicator of CNS Microenvironmental Changes
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Dose-rate and mixed field effects of protons and HZE nuclei on oxidative injury and stem cell plasticity in the CNS
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Replacement Lighting for Research and Training
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Neurochemical and Behavioral Effects of Exposure to Heavy Particles -- NNJ06HD93G
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Mathematical Modeling of Circadian/Performance Countermeasures
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
A Model of Circadian Disruption in the Space Environment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Optical Computer Recognition of Performance Under Stress
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Development of a User Interface for the PVT SelfTest (PST)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Impact of HZE Particles Exposure on Proliferation and Differentiation of Human Neural System Cells
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
HZE Radiation Effects On Neuroinflammation: Role Of Cox-2
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Assessing the Impact of Communication Delay on Performance: An Examination of Autonomous Operations Utilizing the International Space Station
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Selection Studies Retrospective
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Net Habitable Volume Community of Practice
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Ultra-Short Light Pulses as Efficient Countermeasures for Circadian Misalignment and Objective Performance and Subjective Alertness Decrements
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
The ISS Dynamic Lighting Schedule: An in-flight lighting countermeasure to facilitate circadian adaptation, improve sleep and enhance alertness and performance on the International Space Station
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Markers of Susceptibility to Neurobehavioral Decrements in Space Flight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Detection and Prevention of Neurobehavioral Vulnerability to Space Radiation II
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
High LET-radiation induced DNA repair mechanisms in Oligodendrocyte progenitor cells (OPC) in vitro and in vivo - CCSB
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Charged Particle Effects on Neuronal Injury, Plasticity and Neurodegeneration
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Individual Differences in the Neurochemical and Behavioral Response to Exposure to Protons and HZE Particles
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Effects of Space Radiation on Long Term Synaptic Plasticity and Neurogenesis in Normal and Alzheimer's Disease Transgenic Mice
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
The Relation Between Cognitive Injury, Network Stability, and Epigenetic Change Following Exposure to Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Vehicle NHV and Habitability Assessment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Effects of Long-duration Microgravity on Fine Motor Control Skills
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Effects of Long-Duration Spaceflight on Training Retention
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Analog investigation of team resilience over time
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Understanding Key Components of Successful Autonomous Space Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Macrocognition in Teams: Examining and Developing Team Cognitive Processes and Products in the Context of Long Duration Exploration Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Investigate shifts in team cognitive processes over time (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Investigate shifts in team motivation and morale over time (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Developing and Validating Sensor-based Measurement Strategies for Team Member Selection
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Standardized Behavioral Measures for Detecting Behavioral Health Risks during Exploration Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Characterization of Psychological Risk, Overlap with Physical Health, and Associated Performance in Isolated, Confined, Extreme (ICE) Environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Effects of Acute Exposures to Carbon Dioxide upon Cognitive Functions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Mindfulness, Recreation, and Relaxation as a Countermeasure for Long Duration Exploration Missions (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Individualized Real-Time Neurocognitive Assessment Toolkit (Cognition) for Space Flight Fatigue (ISS-12) (NSBRI)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Using Real-Time Lexical Indicators to Detect Performance Decrements in Spaceflight Teams: A Methodology to Dynamically Monitor Cognitive, Emotional, and Social Mechanisms that Influence Performance
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Cyber Partners: Harnessing Group Dynamics to Boost Motivation for More Efficient Exercise
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
STARwatch to Deliver Objective Sleep Measures for Spaceflight Operations (SBIR Phase 2)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Lighting Protocols for Exploration - HERA Campaign
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Psychomotor Vigilance Test (PVT) on ISS (Reaction Self-Test on ISS-12)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Sleep-Wake Actigraphy and Light Exposure During Spaceflight (ISS-12)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Metrics and Methods for Real-Time Task Performance Assessment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Mechanisms of low dose HZE alteration of neuronal-astrocytic coupling: The role of purinergic receptors and calcium signaling
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
The Role of Oxidative Stress and Inflammation on Synaptic Functions After Exposure to Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Molecular Characterization of Choroid Plexus and Hippocampal Damage and Degenerative CNS Risks from Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Particle Radiation-Induced Dysregulation of Protein Homeostasis in the Brain
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Changes in the Neuroproteome Associated with HZE-Induced Impairment of Cognition
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Acute and long term outcomes of simulated deep space radiation exposure on latent viral CNS infection & CNS pathology
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Impact of Space Radiation on Cognition, Synapses and Biomarkers in Aging and Alzheimer's Disease
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Evaluation of the validity, acceptability and usability of bio-mathematical models to predict fatigue in an operational environment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Workload and Scheduling Tools for Long Duration Missions (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Assess Glymphatic Changes for Spaceflight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Future Vehicle Environment (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Post-Mission Behavioral Health Conditions Assessment (RR+Datamining)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Social, Family, and Behavioral Health Support NSCOR
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Astronaut Exploration Factors (Data Mining & Whitepaper)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Meaningful Work for Long Duration Exploration Missions (RR)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Biomarkers as Predictors of Resiliency and Susceptibility to Stress in Space Flight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
A Multi-faceted Approach to Examine Team Adaptation & Resilience within Isolated, Confined, and Extreme Environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Training for Generalizable Skills & Knowledge: Integrating Principles and Procedures
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Crewmember Expectations Training for Long Duration Exploration Missions (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Assessing the Impact of Chronic Sleep Restriction on Sleep and Performance-Associated Regional Brain Activation Using Near-Infrared Spectroscopy (Postdoctoral Fellowship)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Monitoring Technologies COTS and NASA Tools Evaluation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
The Impact of Objectively Measured Sleep Deficiency and Circadian Misalignment on Performance During Spaceflight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Cognitive Performance and Crew Cohesion during Confinement in NASA's Human Research Program Human Exploration Research Analog (HERA)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Radiation Exposures in Space and the Potential of Central Nervous System Effects
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Neurobehavioral and CNS-Related Physiological Changes Following Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
HZE particle exposure-induced improvement of pattern separation in mature mice: alterations in mission-relevant behaviors and neural circuitry
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Family Training and Support Research Requirements
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Software Enabled Therapeutics for Psychiatry, Neurology, and Pain
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Cognition Validation Study in High Performing Healthy Controls at Penn
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Mitigating Neurobehavioral Vulnerabilities to Space Radiation (Follow-On Study)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Cognitive Bias and Decision Making Training (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Mechanisms Underlying Charged Particle-Induced Disruption of CNS Function
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
NASA Specialized Center of Research on Carcinogenesis
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Late CNS Risk Modeling
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
2022 NSCOR: CVD/Late CNS clinical MCM Assessment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
2026 NSCOR: CVD/Late CNS MCM Assessment: Combined Spaceflight Stressors
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Team and Sleep Preliminary Literature Review
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Analog Team/Behavioral Medicine Data Mining
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Cognitive Assessment and Prediction to Promote Individualized Capability Augmentation and Reduce Decrement
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Lighting as a Cognitive and Behavioral Health Countermeasure
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Personality and biological predictors of resiliency to chronic stress among high-achieving adults
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Asynchronous Techniques for the Delivery of Empirically Supported Psychotherapies
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Use of Hypnotic and Alertness Medications in Military Populations (Research Requirements)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Sleep electroencephalography and near-infrared spectroscopy measurements for spaceflight and analogs
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Countermeasures for Neurobehavioral Vulnerabilities to Space Radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Environmental Factors Associated with Sleep Deficiency During Spaceflight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Behavioral Issues Associated with Long Duration Space Missions: Review and Analysis of Astronaut Journals - Extension and ISS-12
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Hadron-induced impairment of Executive Function:role of perturbed neurotransmission and the exacerbating impact of sleep deprivation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Team State Lexical Analysis Software Refinement and Feasibility Testing
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Individual Differences in the Neuronal and Behavioral Response to Exposure to HZE Particles
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Impact of Space-Radiation Induced Alterations on Toxic Protein Accumulation Associated with Neurodegenerative Disease
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Bed Rest Combined with 0.5% CO2 as a Spaceflight Analog to Study Neurocognitive Changes: Extent, Longevity, and Neural Bases
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Mars 600/900 Simulation I: Large Animal Chronic Studies
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Radiation Exposures in Space and the Potential of Central Nervous System Effects Phase II
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Real-Time Estimation of the Effects of a Simulated Long-Duration Exploration Mission on Flight Performance, Workload, and Situation Awareness
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Quantifying and Predicting Operationally-Relevant Performance in a Long-Duration Spaceflight Analog
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
NSCOR for Evaluating Risk Factors and Biomarkers for Adaptation and Resilience to Spaceflight: Emotional Valence and Social Processes in ICC/ICE Environments
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Center for Medical Countermeasures II – Cross Risk
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
2022 NSCOR-CVD/Late CNS: Impact of Combined Spaceflight Stressors
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
NSCOR #2: Acute CNS-Risk Modeling and CM Validation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Mars 600/900 Simulation II: Large Animal Chronic Studies
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Non-Pharm Treatments Verification and Validation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BHP Radiation CNS Standard Measures Table RR
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Cognition Longitudinal Validation Study in High-Performing Healthy Controls at Penn
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
NASA's Behavioral Core Measures (BCM) Cognition Battery vs. WinSCAT: Validation, Norming, and Intra-individual Differences Across Cognitive Domains of Two Spaceflight Cognitive Assessment Tools in Higher Functioning Adults
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Increasing Cognition Administration Order Flexibility
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Spaceflight Habitability Acceptability Questionnaire (SHAQ) Development and Validation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
The Fine Motor Skills and Cognition Test Batteries: Normative Data and Interdependencies
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
ISS HRP Spaceflight Exploration Measures (HFBP) for Gateway
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Generalizability of Operational Feasibility and Acceptability of HFBP Exploration Measures in NEK
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
HFBP Thresholds for Health & Operational Performance Permissible Outcome Limit (POL)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Identification and Validation of HFBP Exploration Measures in HERA for Transport
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Testing of Next Generation of Monitoring Tools for Deep Space & Planetary Exploration
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
HFBP Exploration Measures in HERA for Mars
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
ISS HRP Spaceflight Exploration Measures (HFBP) for Mars Fly-By
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Automated Transcription Maturation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Automated Video Analysis Software Maturation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Quantification of Response to Virtual Reality based Sensory Stimulation for Relaxation and Therapeutic Release in ICE
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Individual and Team Problem-Solving Skills Training for Exploration Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Galactic Cosmic Ray Simulator and Mitigation Project
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
GCR Simulation Dose Rate Studies
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Multi-Model Ensemble Risk Assessment
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Inter-Agency Medical Countermeasures Studies
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Contracted Study CM Validation II (Cross Risk)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Partnership with Dept of Defense to Inform Expeditionary Skills Training for Astronauts
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Sex- and Apo E-specific late CNS and cardiovascular effects of space radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Quantitative Imaging and Biofluid Biomarkers Predictive of Cognitive Toxicity and Cerebro-/Cardiovascular Pathologies following Brain Irradiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Effects of Artificial Gravity on Structural and Functional Plasticity During Head-Down Tilt Bed Rest
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Does Intermittent or Continuous Artificial Gravity Counteract Long Duration Bed Rest Induced Neurocognitive Declines?
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Adaptive Stress Training for Hazardous Conditions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Simulation-based Countermeasure Development to Mitigate Team and System Vulnerabilities During Medical Event Management on Long Duration Space Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Determination/Development of standardization of both Research Facility (e.g., volume, lighting, sound, etc.) & Rodent type to increase reliability & validity of translational research yields related to operational performance
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Central Nervous System, Behavioral Medicine, and Sensorimotor (CBS) Data Mining
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Research Review: Neurobehavioral Biomarkers Performance/Pathway
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS Operational Performance Measures
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Integrated CNS/BMed/SM (CBS) POL/PEL Review and Standard Update
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Determine & Validate CNS/BMed/SM (CBS) relevant operational measures for integrated POLs and identify Research Measures for EM missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS Integrated Risk inflight human monitoring (ISS & Orion DSLOP) for direct and synergistic effects of Acute CNS/BMed/SM (CBS) impacts to measures from which POLs are derived
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS VNSCOR #1: Mechanisms of radiation-induced changes in sustained attention and social processing
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS VNSCOR #1: Responses of the Nervous System to Chronic, Low Dose Charged Particle Irradiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
SHARE/[TBD] GCRsim Exposure Response Study (NRA)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
NHP CNS Radiation/Performance Data Mining
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Research Review: NHP Model Brain Performance Pathways
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Acute CNS Stress Response, Cross-species Homology Study (NRA)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS Brain Regions Functional Modular Structure & Connections of Relevance to Operationally-Relevant Performance (RFP)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Future research (NSCOR) -- potential topics include RBEs, Glial cell response, stress response, cross-species homology, animal mood/social/cognition, sleep/stress/cognition, neural plasticity, dose rate effect for multiple measures
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Integration of Research Findings from ongoing research (11 NRAs, 1 NSCOR; including epigenetics, synaptic function, neurobehavioral, neuroproteome, behavior & neural circuitry, biomarkers, sleep deprivation, affect/social) to guide development of PELs
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Computational Modeling for CBS Synergistic and Order Effects of Radiation Exposure, Stress, and Hindlimb Unloading to Identify Operationally-Relevant Brain Physiology, Biomarkers, and Performance
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Acute CBS Integrated Risks, Synergistic and Dose-Effects Study (NRA)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Integrative Risk Data Mining: Individual Sensitivities and Countermeasures
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
BioNutritional Countermeasures Data Mining
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS Integrated Risk Review & Trade Study
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Identification, Development, and Validation of Countermeasures to Counter Synergistic Effects of Space Radiation on CNS/BMed/SM (CBS) Risk Areas (NRA)
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Research Review: Human Capabilities Assessment for Autonomous Missions (HCAAM) Intelligent System: Monitoring & Countermeasures Performance Pathways
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CNS/BMed/SM (CBS) CM2: Identification, Development, and Validation of Countermeasures to Counter Synergistic Effects of Space Radiation on Risk Areas
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS Biomarker and Countermeasure (CM) Flight Update/Validation Based on Biomarkers and Operationally-Relevant Performance Measures
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS Data Integration and POL/PEL Standard Update
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Gamma-tocotrienol as a countermeasure against high-energy charged particle-induced carcinogenesis, cardiovascular disease, and central nervous system effects
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
CBS VNSCOR #2: Oxidative stress and the neuroconsequences of spaceflight environment - Immune dysregulation and antioxidant dietary countermeasure efficacy
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS VNSCOR #2: Probing the synergistic effects of radiation, altered gravity and stress on behavioral cognitive and sensorimotor functions to predict performance decrement in astronauts
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
CBS VNSCOR #2: Impact of inflight stress and sleep disturbances on brain function, neural communication and inflammation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Variation in CNS damage signaling and blood sentinels of neuropathology after exposure to space radiation.
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Effects of mixed beam irradiation in the presence and absence of Hindlimb Unloading on behavioral and cognitive performance and metabolic pathways in pertinent brain regions in WAG rats.
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Astrocytes as key mediators of central nervous system responses to space radiation
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Towards a Real-Time Estimate of Circadian Phase During Spaceflight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Characterizing the Baselines of Sleep Quality, Cognitive / Operational Performance, Immune Function, and Intracranial Fluids for Deep Space Expeditions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Temporal Nature of Cognitive and Visuospatial Brain Domain Changes during Long-Duration Low-Earth Orbit Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Mapping peripheral immune signatures of mouse and human responses to space radiation for biomarker identification
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Habitability and Sensory Stimulation for Long-Duration Missions
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
The impact of human spaceflight on clonal hematopoiesis
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Measuring Transcutaneous Partial Pressure of Carbon Dioxide (PCO2) to Estimate Arterial PCO2 during Spaceflight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
Recovery Timeline of Spaceflight-Induced Central Nervous System Changes
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
Long-Term Brain Structural and Functional Consequences of Spaceflight
Common Item(s)
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
BMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
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