HRR - Task - Detection & Prevention of Neurobehavioral Vulnerability to Space Radiation

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Detection & Prevention of Neurobehavioral Vulnerability to Space Radiation (Completed)

Last Published: 03/26/21 03:34:00 PM (Central)

Task Book: Entry
Principal Investigator: Hienz, Robert

Short Title: Neurostructural Changes Radiation

Responsible HRP Element: Behavioral Health and Performance

Collaborating Org(s):

National Space Biomedical Research Institute (NSBRI)

Funding Status: Completed - Task completed and produced a deliverable

Procurement Mechanism(s):

Solicited

Aims:

1. To assess the effects of space radiation across a range of cognitive/behavioral functions in rodents. Performance measures include assessments of general motor function and speed, fine motor control, inhibitory control (impulsivity), timing, short-term memory, spatial working memory, learning and selective attention, motivation, and basic sensory function.

2. To assess the long-term effects of radiation across a range of cognitive/behavioral functions via extended post-exposure testing for potential performance deficits.

3. To assess both the acute and long-term effects of radiation on the neurochemical mechanisms underlying changes in cognitive/behavioral functions by examining the integrity of the neurotransmitter systems known to mediate those neurobehavioral functions found impaired.

Resources (None Listed)

Deliverables (1)

Category: Risk Characterization, Quantification
Subcategory: Evidence or Risk Characterization

Description:
Summary report regarding neurobehavioral vulnerability to space radiation.

Internal Customers:
Behavioral Health and Performance
External Customers:
None

Mappings

Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders

BMed-101: We need to identify, quantify, and validate the key selection factors for astronaut cognitive and behavioral strengths (e.g., resiliency) and operationally-relevant performance threats for increasingly Earth independent, long-duration, autonomous, and/or long-distance exploration missions.

BMed-108: Given each crewmember will experience multiple spaceflight hazards simultaneously, we need to identify and characterize the potential additive, antagonistic, or synergistic impacts of multiple stressors (e.g., space radiation, altered gravity, isolation, altered immune, altered sleep) on crew health and/or CNS/ cognitive functioning to develop threshold limits and validate countermeasures for any identified adverse crew health and/or operationally-relevant performance outcomes.

Detection & Prevention of Neurobehavioral Vulnerability to Space Radiation

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Risk Approach Plans (1)

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Common Item(s)
	Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders